Period 1. (01 September 2013 - 28 February 2015)

Organization of conference

  • Il contributo del modello di grande animale nella fase pre-clinica e clinica della medicina traslazionale: un punto d’incontro tra medicina veterinaria ed umana. Fondazione Iniziative Zooprofilattiche e Zootecniche Brescia (Provider ECM Regione Lombardia RL0167) 20 Febbraio 2015, 100 participants.
  • From research to therapy for the treatment and prevention of diabetes. Public event for lay people/ students, 31-10-2014 Chamber of Commerce Cremona.

Participation on conferences/scientific meetings

  • Galli, C. The use of the pig in pre-clinical and clinical xenotranplantation , XXI Annual Convention Associazione Italiana per le Scienze degli Animali da Laboratorio (AISAL),Torino 23-25 October 2014, 120 participants. Oral communication.
  • Perota A, Lagutina I, Duchi R, Quadalti C, Turini P, Crotti G, Colleoni S, Lazzari G, Peverali F, Lucchini F, Galli C. Targeted RMCE-live piglets generated by SCNT following sequential double site-specific gene modifications of a porcine EGFP line. 12th Transgenic Technology Meeting (TT2014), Edinburgh, Scotland, United Kingdom, 6–8 October 2014, pp 880-881.
  • Genetic Engineering and Somatic Cell Nuclear Transfer to Generate Large Animal Models:Industrial Biotechnology, PhD Meeting University of Milano Bicocca, October 13-15, 2013, Verbania Pallanza.
  • Genetic Engineering and Somatic Cell Nuclear Transfer to Generate Large Animal Models: Industrial Biotechnology, PhD Meeting , May 14, 2014, University of Insubria, Varese.
  • Genetically modified pigs and large mammals as a pre-clinical tool for translational medicine. PhD Meeting University of Milano Bicocca 28-05-14.
  • Genetic Engineering and Somatic Cell Nuclear Transfer to Generate Large Animal Models: Industrial Biotechnology, PhD Meeting CNR Pavia 17-06-14.
  • Gianello, P. Islet Xenotransplantation: are we ready for clinical islet xenotransplantation? Use of a subcutaneous monolayer cellular device containing pig islets to treat diabetic primates without Immunosuppression. The 1st international conference of clinical islet xenotransplantation (ICCIX)- endorsed by IXA, Osaka, Japan, 9 November 2013. Oral communication.
  • Gianello, P. Islet Xenotransplantation: are we ready for clinical islet xenotransplantation? Use of a subcutaneous monolayer cellular device containing pig islets to treat diabetic primates without Immunosuppression. 12th congress of the International Xenotransplantation Association, Osaka, Japan, 10-13 November 2013. Oral communication.
  • Gianello, P. Traitement du diabète : espoir dans la Xénotransplantation. XIVème Colloque : Médecins généralistes en collaboration avec L’ECU-UCL et les Cercles de la province du Luxembourg, Villers-devant-Orval, Belgium, 12-13 April 2014. Oral communication.
  • Gianello, P. Encapsulation Technology as Paradigm for Bioengineering Xenogeneic Organs to Escape Immunoregulation. World Transplant Congress, San Francisco, California, USA, 26-31 July 2014. Oral communication.
  • E. Cozzi, R. Elliott, P. Gianello, B. Hering, S. Matsumoto, P. O’Connell, C.G. Park, G. Korbutt, R. Toenjes, W. Wang. Update on national regulatory frameworks pertinent to clinical islet xenotransplantation; with emphasis on countries with active research programs on islet xenotransplantation. 2nd international congress on clinical islet xenotransplantation (ICCIX) - endorsed by IXA, San Francisco, California, USA, 1 Augustus 2014.
  • D. Cooper, R. Bottino, P. Gianello, M. Graham, W. Hawthorne, O. Korsgren, C.G. Park, C. Weber. Pre-clinical efficacy and complication data required to justify a clinical trial. 2nd international congress on clinical islet xenotransplantation (ICCIX) - endorsed by IXA, San Francisco, California, USA, 1 Augustus 2014.
  • B. Hering, P. O’Connel, R. Elliott, P; Gianello. Patient selection. 2nd international congress on clinical islet xenotransplantation (ICCIX) - endorsed by IXA, San Francisco, California, USA, 1 Augustus 2014.
  • P. Gianello. Islet Xenotransplantation: are we ready for clinical islet xenotransplantation? Use of a subcutaneous monolayer cellular device containing pig islets to treat diabetic primates without immunosuppression. 1st International Conference on Immune Response to Biosurfaces: Mechanisms and Therapeutic interventions, Chana, Crete, Greece, September 27 – October 2 2014.
  • P. Gianello. Xenotrapianto di isole pancreatiche suine nei pazienti con diabete di tipo 1 : siamo pronti per la clinica ? Dalla Ricera Alla Terapia Per La Cura e la prevenzione del diabete. Cremona, Italy, October 31, 2014. Oral communication.
  • Puskas, L. Digital PCR to determine the number of transcripts from single neurons. MicroRNAs & Single Molecule Biology/Genome Editing Europe Symposia. Peterhouse College, University of Cambridge, Cambridge, United Kingdom, November 3-4 2014. Oral communication.
  • AVD, BIO International Convention, partnering, San Diego/USA, 23-24/06/14
  • GCU Annual Research Day, 6 June 2014. Public dissemination.

Publications

  • Perota A, Lagutina I, Duchi R, Turini P, Crotti G, Colleoni S, Lazzari G, Lucchini F, Galli C. Live piglets generated by somatic cell nuclear transfer following targeting of a porcine enhanced green fluorescent protein line mediated by zinc-finger nucleases to establish cloned hygromycin-resistant primary cell lines suitable for cre-mediated recombinasemediated cassette exchange. Reproduction, Fertility and Development 26, 1, 2014, Proceedings IETS, p221, abst 215.
  • Kim MK, Choi HJ, Kwon I, Pierson RN 3rd, Cooper DK, Soulillou JP, O'Connell PJ, Vabres B, Maeda N, Hara H, Scobie L, Gianello P, Takeuchi Y, Yamada K, Hwang ES: Kim SJ, Park CG . The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of xenocorneal transplantation.; International Xenotransplantation Association. Xenotransplantation. 2014 Sep-Oct;21(5):420-30. doi:10.1111/xen.12129. Epub 2014 Sep 1.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no. 601827