Period 3. (01 September 2016 - 31 August 2017)

Publications

  • Szebeni, J. G., Tancos, Zs., Feher, L. Z.,Alfoldi, R., Kobolak, J., Dinnyés, A., Puskás G. L. Real architecture For 3D Tissue (RAFTTM) culture system improves viability and maintains insulin and glucagon production of mouse pancreatic islet cells. Cytotechnology, 69(2), 359-369. 27. March 2017 doi: DOI 10.1007/s10616-017-0067-6
  • Mourad NI, Crossan C, Cruikshank V, Scobie L, Gianello P. Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets. Xenotransplantation, 2017 Jul;24(4). doi: 10.1111/xen.12311. Epub 2017 Apr 26.
  • Mourad NI, Perota A, Xhema D, Galli C, Gianello P. Transgenic Expression of Glucagon-Like Peptide-1 (GLP-1) and Activated Muscarinic Receptor (M3R) Significantly Improves Pig Islet Secretory Function. Cell Transplant. 2017 May 9;26(5):901-911. doi: 10.3727/096368916X693798. Epub 2016 Nov 22.
  • Apolline Salama, Mathilde Mosser, Xavier Lévêque, Andrea Perota, Jean-Paul Judor, Corentin Danna, Sylvie Pogu, Anne Mouré, Dominique Jégou, Nicolas Gaide, Jérôme Abadie, Olivier Gauthier, Jean-Paul Concordet, Stéphanie Le Bas-Bernardet, David Riochet, Ludmilla Le Berre, Jérémy Hervouet, David Minault, Pierre Weiss, Jérôme Guicheux, Sophie Brouard, Steffi Bosch, Irina Lagutina, Roberto Duchi, Giovanna Lazzari, Emanuele Cozzi, Gilles Blancho, Sophie Conchon, Cesare Galli, Jean-Paul Soulillou and Jean-Marie Bach:  Neu5Gc and α1-3 GAL Xenoantigen Knockout Does Not Affect Glycemia Homeostasis and Insulin Secretion in Pigs. Diabetes 2017 Apr; 66(4): 987-993. https://doi.org/10.2337/db16-1060
  • Mourad, N.I. & Gianello, P.: Gene Editing, Gene Therapy, and Cell Xenotransplantation: Cell Transplantation Across Species. Curr Transpl Rep (2017) 4: 193. https://doi.org/10.1007/s40472-017-0157-6
  • Mourad, N.I. & Gianello, P.: Xenoislets: porcine pancreatic islets for the treatment of type I diabetes.  Current Opinion in Organ Transplantation (Accepted)

Publications (abstract)

IETS 2017

  • Perota A, Lagutina I, Quadalti C, Duchi R, Turini P, Crotti C, Colleoni S, Conchon C, Concordet JP,Lazzari G, Soulillou JP, Galli C: Single step gene editing of three xenoantigens in porcine fibroblasts using programmable nucleases. Reproduction, Fertility and Development 29(1) 108 – 216. DOI 10.1071/RDv29n1abs

 

Participation to conferences/scientific meeting

  • 06/10/2016: Prof. Galli Cesare. Ovum pick-up and production of embryos in dairy industry. Scientific Symposium - Reproduction of Domestic Animals. Divčibare, Serbia
  • 14/11/2016: Prof. Cesare Galli. First results of oocyte maturation and In-Vitro-Fertilisation (IVF) in Sumatran and northern white rhinoceroses. 15th International Elephant & Rhino Conservation and Research Symposium, Singapore
  • 14/01/2017: Prof. Cesare Galli. Single step gene editing of three xenoantigens in porcine fibroblasts using programmable nucleases. IETS 2017, Austin TX, USA
  • 13-17/08/2017: Prof. Galli Cesare: Transgenic Animal research Conference XI, Tahoe CA, USA

 

Organization of conference

  • TransLink – Xenoislet Joint Conference - Joint “Research on animal-derived products for use in the clinic – Results from EU collaborative projects” dissemination event, 9th November 2016, London, UK. This event bringed together two international projects, TransLink (www.translinkproject.com) and XenoIslet, funded by the European Union’s Seventh Framework Programme for Research and Technological Development. The conference aimed to promote the international exchange of the latest concepts, innovative techniques and results in the field of  cardiovascular valve transplantation, glycoimmunology,  pancreatic islets  and innovative diabetes treatment,offering participants the opportunity to
interact
with
a
number
of
outstanding scientific leaders and researchers. Further information and programme: http://www.translinkproject.com/translink-xenoislet-joint-conference/
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no. 601827